Clinical Screening Tool

EDES-10

General Endocrine Disruptor Exposure Screen

The EDES-10 is a clinician-guided exposure screening tool for use with general adult patients across primary care, functional medicine, occupational health, and allied health settings. It covers the most practically relevant everyday exposure domains — food and packaging, personal care products, home environment, and nutritional resilience — in a single, time-efficient screen suitable for routine consultations.

Version v3 | Last updated: June 2026

Why screening for EDC exposure matters in the general population

Endocrine-disrupting chemicals are present across the environments most people navigate every day — food packaging, household products, personal care items, dust, and water. Individually, many exposures appear modest. Cumulatively and over time, they represent a chronic, low-level hormonal burden that clinical practice rarely addresses in a structured way.

Major endocrine societies, the WHO, and the UNEP have identified EDC exposure as a significant public health concern with links to reproductive dysfunction, metabolic disruption, thyroid pathology, and developmental harm. Yet most clinical encounters lack any structured route for identifying where a patient’s exposure load sits, or which domains are most amenable to change.

The EDES-10 addresses this gap. It does not require specialist knowledge and is not intended to produce a diagnostic conclusion. Its purpose is to open a structured, evidence-informed conversation — one that translates awareness into practical, prioritised action.

Who this tool is for

The EDES-10 is intended for use with adult patients across a wide range of clinical settings. It is particularly relevant in:

  • Primary care and general practice with an interest in lifestyle or preventive medicine
  • Functional medicine, integrative medicine, and naturopathic practice
  • Occupational health settings where environmental exposures are a routine concern
  • Preconception and reproductive health consultations (recommended alongside the EDES-W)
  • Chronic disease management where hormonal or metabolic factors may be relevant
  • Any consultation where a patient expresses concern about environmental exposures

The tool is designed to be administered by or in consultation with a qualified healthcare professional. It is not intended for unsupported self-assessment.

Clinical disclaimer: EDES tools are educational screening instruments designed to support structured clinical conversations about environmental chemical exposure. They are not diagnostic tools, do not replace clinical judgement, and are not formal clinical guidelines. Results should always be interpreted in the context of the individual patient and the clinician’s professional assessment.

The Screen

The EDES-10 contains 24 scored items across four sections, plus two unscored readiness items. Completion time is approximately 6–8 minutes.

SectionDomainItemsCount
Section AFood, Drinks & PackagingA1–A88 items
Section BPersonal Care ProductsB1–B44 items
Section CHome EnvironmentC1–C77 items
Section DNutritional ResilienceD1–D55 items
Section ERisk Perception & Readiness (unscored)E1–E22 items

Full scored items: 24 | Maximum total score: 72 | Each item rated 0–3

Download & Print

The EDES-10 is available as a complete clinical package. All documents are formatted for clean printing and immediate clinical use:

EDES-10 Clinical Tool (Questionnaire)

Printer-ready questionnaire — for in-consultation completion

EDES-10 Clinician's Interpretation Guide

Scoring, domain flag logic, counselling priorities, and chart note template

EDES-10 Patient Handout

Brief, accessible summary of key reduction actions for patient distribution

Tip: Use the individual PDF buttons above to download each document separately.

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Evidence Note

The EDES tool family is grounded in peer-reviewed endocrinology, reproductive toxicology, and developmental biology literature.

Visit the Evidence Base

Implementation Support

For patient-facing handouts, counselling guides, and expanded clinical education materials.

Visit Endocrine Resilience

Expert Review & Feedback

We welcome feedback from healthcare professionals, researchers, and public health practitioners.

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